PROCR and cerebral malaria: To assess the role of FcγRIIIb binding to antibodies targeting ICAM-1 binding DBLβ domains in protection from cerebral malaria, we measured antibody-dependent neutrophil phagocytosis (ADNP) of IE selected for expression of 3D7VAR04 (Pfd1235w), which co-binds to ICAM-1 and EPCR, and IT4VAR13, which co-binds to ICAM-1 and CD36 (Fig. 4).