ACSL4 and non-small cell lung carcinoma: For instance, it has been discovered to promote ferroptosis in NSCLC by modulating SLC7A11/GPX4, and it can induce ferroptosis in glioma cells by the ACSL4/GPX4 pathway, thus providing antitumor benefits (Liu et al. 2022b; Hacioglu and Kar 2023).