Thus, the proinflammatory capacity of pDCs and CXCR3+CCL25+ T cells during the mature phase of AIP is much greater than that of cDCs and CXCR3+CCL25+ T cells during the early phase of AIP, and this greater capacity translates into a greater potential to support a more robust pancreatitis. This evidence concerns the gene CCL25 and autoimmune pancreatitis.