TLR3 and autoimmune pancreatitis: Finally, it should be noted that the cDCs isolated from poly(I:C)-treated mice produced higher levels of type I IFNs and chemokines upon stimulation with poly(I:C) than cDCs from untreated mice, suggesting that cDCs present in the milieu characterizing the early phase of AIP have gained enhanced responsivity to TLR3 stimulation.