In the final series of the experiments, we investigated the question of whether the chemokines comprising the positive feedback loop noted above and responsible for pancreatic pDC and CXCR3+ T cell infiltration in the MRL/MpJ model of AIP are also present in human AIP/IgG4-RD. Here, CXCR3 is linked to immunoglobulin G4-related sclerosing disease.