GRB2 and myeloid sarcoma: The top-ranked genes like PPP2CB and PPP4R2, encode for part of protein complexes and thus shared high values of graph centrality metrics (degree, betweenness, and eigenvector centrality), Among other genes with topological relevance that were also significantly associated with response to NTZ, we identified two genes like LRP6 (p = 0.045) and GRB2 (p = 0.023) which have been already implicated in MS (see Discussion).