The overall sample included 165 participants, that is, 64 patients with AD (age: 73.1 ± 8.3 years, 34 females, 30 males), 82 patients with 4RT (age: 71.5 ± 7.0 years, 33 females, 49 males) of which 58 were diagnosed with PSP and 24 with CBS, and 19 healthy controls (age: 67.9 ± 11.1, 8 females, 11 males). This evidence concerns the gene CBS and Alzheimer disease.