TP53 and neoplasm: i.v. injected a triangle DNA origami nanokite to deliver linear tumor suppressor gene p53 and DOX to mice bearing multidrug‐resistant tumors (Figure 7c).[83] The nanokites associated with ECs in the tumor (Figure 7d), but there was no proof whether they reached the tumor cells where the cargoes should exert their anti‐cancer efficacy.