i.v. injected a triangle DNA origami nanokite to deliver linear tumor suppressor gene p53 and DOX to mice bearing multidrug‐resistant tumors (Figure 7c).[83] The nanokites associated with ECs in the tumor (Figure 7d), but there was no proof whether they reached the tumor cells where the cargoes should exert their anti‐cancer efficacy. The gene discussed is TP53; the disease is cancer.