This study therefore investigated the alterations in both GLP-1 and GLP-2 levels after DJB operation in a Type 2 diabetic rat model under feeding and fasting conditions and examined the changes in STR signals (T1R2/T1R3/Gα-gustducin [G protein alpha gustducin]) and glucose transporters (SGLT1/GLUT2) in the DJB-remodelled duodenum and jejunum. The gene discussed is GCG; the disease is type 2 diabetes mellitus.