GLIS3 and major depressive disorder: For major depressive disorders, per one-unit increase in genetically predicted log odds of T1D as measured by the GLIS3 cis instrument was associated with a 7% increase in odds using the secondary weighted median method only (OR = 1.07; 95% CI = 1.00–1.15; P = 0.032), but this association did not persist following adjustment for multiple testing (adjusted P = 0.128).