IL4 and allergic asthma: Almeida et al. found that at concentrations of 20, 50, and 200 mg/kg, Mandevilla longiflora reduces inflammatory cells, IL-13, IL-5, IL-4, IgE, and LT-B4 in BALF, improving airway inflammation in the murine model of allergic asthma comparable to dexamethasone [105].