IGHE and asthma: Heo et al. demonstrated that the aqueous extract of Camellia sinensis at the concentration of 25 μg/ml exerts antiasthmatic activity by alleviating asthma-related cytokine activity through increasing the expression of TGF-β, IFN-γ, and IL-10 and by decreasing the expression of inflammatory cytokines IL-4, IL-13, and IgE in the lungs [65].