Attempts to find correlations among CCN4, VCAM1, GM-CSF, MMP3, and DAS28-ESR levels with TSH, LDL, ALKP, age, and BMI values in patients with RA indicated generally significant statistical correlations, except for CCN4 with ALKP, and MMP3 with ALKP. This evidence concerns the gene MMP3 and rheumatoid arthritis.