Androgen use and male gender are often related to catenin beta 1-mutated hepatic adenomas, which have a higher risk of malignant transformation and warrant more aggressive treatments, including surgery or interventional radiology treatment.6,7 Hepatic adenomatosis (≥10 adenomas) has an even higher risk of spontaneous rupture, hemorrhage, and malignant transformation. Here, CTNNB1 is linked to adenoma.