Specifically, GLP-1 RAs reduced the risk of death from cardiovascular causes by 10% (RR: 0.90; 95% CI: 0.83-0.97; P = 0.004) and reduced the risk of stroke (fatal or nonfatal) by 15% (RR: 0.85; 95% CI: 0.77-0.94; P = 0.001). This evidence concerns the gene GLP1R and Stroke.