At the molecular level, crucial steps toward metastasisformation include cell structural changes, alteration of adhesion,and reorganization of cytoskeletal proteins involved in motility.Hence, this study investigates the potential of dietary xenoestrogensto impact selected aspects of breast cancer cell mechanotransduction.Taking the onset of the metastatic cascade as a model, experimentsfocused on cell-matrix adhesion, single-cell migration, and adaptationof cell morphology. This evidence concerns the gene DNM2 and breast carcinoma.