Studies that did not find an association between plasma myostatin levels and insulin sensitivity by hyperinsulinemic‐euglycemic clamp or insulin resistance by HOMA‐IR or HOMA2‐IR among adults of a similar mean age and BMI did not exclude adults with end‐organ dysfunction and measured myostatin levels by immunoassay (Toloza et al., 2018) or did not exclude adults on metformin and did not measure myostatin levels fasting (Brandt et al., 2012). This evidence concerns the gene INS and Insulin resistance.