CTSB and Sepsis: This was somewhat expected because several acute phase proteins (APPs) have protective activities in sepsis and sepsis-like models (Libert et al, 1994a; Hochepied et al, 2000; Van Molle et al, 1997; Dalli et al, 2014; Libert et al, 1996; Janz et al, 2013; Larsen et al, 2010).