In sepsis, failure of peroxisome proliferator-activated receptor α (PPARα) and glucocorticoid receptor (GR), which control these processes, causes accumulation of FFAs, glycerol, amino acids and lactate, as well as shortage in ketones and glucose (Vandewalle et al, 2021; Van Wyngene et al, 2020). This evidence concerns the gene NR3C1 and Sepsis.