A significant overlap was observed between the genes targeted by SF3B1MUT-related ASEs in the ICGC CLLE-ES and subset #2 cases, including BRD9, DLST, and SERBP1. Furthermore, we analyzed a set of 1019 cancer cell lines from CCLE [28], including 4 SF3B1MUT cell lines, and detected significant exon usage differences within six of the ncBAF complex-related ASEs identified in the comparison of SF3B1MUT and SF3B1WT subset #2 cases (Supplementary Fig. 6). Here, DLST is linked to cancer.