RUNX1 and acute lymphoblastic leukemia: Similar to de novo B-ALL, cytogenetic subtypes with the best OS post-relapse were ETV6::RUNX1 and Trisomy 4 + 10 with 5-year OS of 74.4 ± 3.1% and 70.2 ± 3.6% respectively, while those with the worst outcomes were hypodiploid (14.2 ± 6.1%), and KMT2A-R (31.9 ± 7.7%).