TNF and neoplasm: To further confirm a role for CBFβ in modulating tumour cell sensitivity to both CAR-T cell and TNF-mediated death, we carried out competitive cell death assays by mixing E2-Crimson-labelled sgNT cells with unlabelled sgCbfb cells a 1:1 ratio and exposed the mixed population to CAR-T cells, or recombinant TNF (Fig. 1K).