MPO and necrotizing enterocolitis: Chen et al. [193] also showed that elevated expression of miR-141-3p may ameliorate the necrotizing enterocolitis by targeting the motor neuron and pancreas homeobox 1 (MNX1) gene, which controls the expression of oxidative stress markers such as (SOD, MPO, and MDA) and inflammatory mediators such as (IL-1β, IL-6, and TNF-α).