When considering the seven clusters containing at least one predicted WT1-specific TCR (Table 3; Fig. 7B), the majority (39 out of 42) were made up only of sequences that were found in AML patients (Supplemental material S9), indicating disease-specificity and (predictive) relevance of WT1-specific TCRs in AML. Here, WT1 is linked to acute myeloid leukemia.