TNF and cancer: Through topological analysis, key components such as quercetin, beta-sitosterol, kaempferol, luteolin, and naringenin were screened out according to the degree value, which was mostly related to anti-inflammation, antioxidation, and antitumor.[5] Studies have shown that Tiaoqi Xiaowei decoction regulates cancer pathway, PI3K-Akt signaling pathway, interleukin-17 signaling pathway, cancer signaling pathway, tumor necrosis factor signaling pathway, and other pathways by acting on core targets such as AKT1, TP53, VEGFA, TNF, IL6, and PTGS2.