The expression of all 8 CCT members was increased in cholangiocarcinoma, colon adenocarcinoma, esophageal carcinoma, head and neck squamous cell carcinoma, liver hepatocellular carcinoma, LUAD, LUSC, prostate adenocarcinoma, rectum adenocarcinoma, and stomach adenocarcinoma, except for CCT6B. The gene discussed is FLVCR2; the disease is cholangiocarcinoma.