NFKB1 and colitis: The E. fissicatena group is a gut pathogen.[28] Liu et al pointed out that Bitter Panax ginseng flowers can target regulatory NF-KB signaling to suppress pathogenic bacteria, including the E. fissicatena group, thereby reducing colitis.[29] Another study by Li et al[28] also revealed that Rabdosia Serra improved colitis progression in mice by reducing the abundance of the E. fissicatena group.