While primarily known for its role in eosinophil-mediated immune responses, recent investigations have explored its association with the inflammatory milieu observed in schizophrenia, offering insights into its potential utility as a biomarker for disease monitoring and characterization.[20,21] Studies examining peripheral biomarkers in schizophrenia have reported fluctuations in ECP levels in affected individuals. Here, RNASE3 is linked to schizophrenia.