DGUOK and neoplasm: miR‐145‐5p inhibitor abolished the ability of DGUOK‐AS1 KD to inhibit liver tumor growth, metastasis, and TC and TG levels, and SIX1 KD or SIX1 KO abrogated the ability of DGUOK‐AS1 and miR‐145‐5p inhibitor to promote liver tumor growth, metastasis, and TC and TG levels, suggesting that DGUOK‐AS1/miR‐145‐5p axis regulates tumor growth, metastasis and DNL via SIX1.