In liver cancer cells, the insulin/DGUOK‐AS1/miR‐145‐5p axis did not alter the histone acetylation at the SIX1 promoter (Figure S8A, Supporting Information), suggesting that the insulin/DGUOK‐AS1/miR‐145‐5p axis may not regulate SIX1 expression at the transcriptional level. Here, DGUOK-AS1 is linked to liver cancer.