]The cytokine storm plays a critical role in HLH and is characterized by the expression of IFN‐γ, IL‐6, TNF‐α, and IL‐1β.[9, 10] Therefore, we first evaluated the inhibitory effect of anti‐CD41‐PLT‐VP16 on cytokine storms. The gene discussed is TNF; the disease is hemophagocytic syndrome.