In AD, we have selected 5 genes, which are DCN (AUC = 0.7075), TNF (AUC = 0.6516), MLKL (AUC = 0.6304), IL1B (AUC = 0.5638), and IL18 (AUC = 0.5626) (Figures 10A, B). This evidence concerns the gene IL18 and Alzheimer disease.