Simple linear regression analyses showed that CD4+ Th1, Th2, Th9, and Th17 levels, as well as the expression levels of IL-4 from CD4+ Th2 cells and IL-13 from CD4+ Th2 and Th22 cells presented a trend towards an association with the development and/or persistence of PCC, in comparison with Mild cohort (Table 2A). The gene discussed is IL4; the disease is adrenal gland pheochromocytoma.