These factors included diabetes (P = 0.014), liver cirrhosis (P = 0.001), elevated C-reactive protein (CRP) levels on POD-3 (P = 0.002) and POD-7 (P < 0.001), a pre-operative serum prealbumin level below 0.15 g/L (P = 0.001), prolonged operation time (P = 0.025), intraoperative bleeding exceeding 120 ml (P = 0.009), vascular reconstruction (P = 0.001), a soft pancreas texture (P < 0.001), and a main pancreatic duct diameter of ≤3 mm (P = 0.011). This evidence concerns the gene CRP and diabetes mellitus.