SHANK3 and autism: Furthermore, we discovered that autism‐associated Shank3 mutations in dogs abolished the interbrain neural coupling and joint attention during human–dog interactions, and these phenotypes were rescued by a single dose of the psychedelic lysergic acid diethylamide (LSD), which reopens the critical period of social reward learning in mice.[13] Our findings have implications for understanding the neural mechanisms underlying the effective social interaction between family dogs and humans and suggest a potential of LSD in ameliorating the social deficits in ASD.