In parallel, the LOX and CYP450 pathways were also activated after ischemic stroke based on the significant increase of 9-HODE, 9-KODE, 13-HODE, 12-HETE, 12-KETE, 15-HETE, 13-HOTrE, 12-HEPE, and 9-HETE, 11-HETE, 12(13)-EpOME, respectively (Figures 7B and S8). This evidence concerns the gene LOX and ischemic stroke.