Cardiomyocyte‐specific PKM2 deficiency increased apoptosis of cardiomyocytes due to loss of PKM2 transcriptional activity, leading to the development of fibrosis and dilated cardiomyopathy in an age‐dependent manner in mice (Lorenzana‐Carrillo et al., 2022). This evidence concerns the gene PKM and dilated cardiomyopathy.