Although our results are based on a single tumor sample, the significant correlation between Vim and ZEB1 expression in the TNBC cohort and the consistent ZEB1 expression in all spindle metaplastic components of MpBC, which is pathologically associated with EMT, substantiate the biological importance of ZEB1 in acquiring Vim expression and the EMT phenotype in breast cancer. The gene discussed is ZEB1; the disease is breast cancer.