VIM and cancer: We examined TFs that sequentially and significantly upregulated as cancer cells progressed through the EMT course, which correlated with the increasing expression of VIM. We discovered a highly significant correlation of high VIM expression levels with the NESs of the EMT pathway, as well as the EMT score [21], which provides strong support for the use of high VIM expression as an indicator of EMT status (Fig. 5A and C, Supplementary Table S4, and Supplementary Fig. S10).