RRM2 and hepatocellular carcinoma: Additionally, the Kaplan-Meier plot showed an association between RRM2 CNV and a shorter OS (log-rank test, P = 0.0156), a shorter DSS (log-rank test P = 0.0284), and a shorter progression free survival (PFS, log-rank test P = 6.241E-3) in HCC patients (Fig. S2D-F).