Though defects in several genes coding for interaction partners of Densin-180 (CTNNB1; coding for β-catenin; CTNND2; coding for δ-catenin; SHANK2, SHANK3) are associated with neurodevelopmental disorders (NDD) in humans15–18, LRRC7 has not yet been firmly established as an aetiological gene in humans. The gene discussed is LRRC7; the disease is neurodevelopmental disorder.