APOE and early-onset autosomal dominant Alzheimer disease: To summarize, statin use in Alzheimer’s disease is influenced by sex and race/ethnicity.495 In a META study, Avgerinos et al. found that application of antibodies against Aβ in Alzheimer’s disease did not show differences in sex and apoE genotype.496 The Multidomain Alzheimer’s Prevention Trial and the Finnish Geriatric Intervention Study for the Prevention of Cognitive Impairment and Disability did not assess variations in outcomes based on sex.497,498 Therefore, the study of sex differences related to the treatment of Alzheimer’s disease patients remains to be explored more widely.