Indeed, GWASs have associated PDE4B SNPs with PTSD (Gelernter et al., 2019; Meier et al., 2019; Nievergelt et al., 2024), as well as schizophrenia (Trubetskoy et al., 2022) and substance use disorders (Hatoum et al., 2023) that are often comorbid with it (Kessler et al., 1995). The gene discussed is PDE4B; the disease is post-traumatic stress disorder.