LUT can inhibit Cd-induced ROS generation, enhancing intestinal function and microbiota, increasing barrier protein expression, reducing blood lipopolysaccharides, and inhibiting the TLR4/NF-κB inflammatory pathway, thus preventing the progression from simple steatosis (SS) to nonalcoholic steatohepatitis (NASH) (Wang et al., 2018). This evidence concerns the gene NFKB1 and metabolic dysfunction-associated steatohepatitis.