TIMD4 and endometriosis: Of the key genes, Apoe appeared to have an implicit role in LpM function in endometriosis; Apoe+ Tim4− LpM were significantly more abundant in mice with endometriosis compared to those without (Fig. 4C; P < 0.01), albeit the mean fluorescence intensity was higher in Tim4+ LpM derived from mice with endometriosis (Fig. 4D).