Among cancer plasmids without TAA or TAA alone treatments, pairwise comparison with the negative control found that SB/AKT/NRas + saline had the most differentially expressed genes (550 after multiple comparisons correction), followed by SB + TAA (470) and SB/AKT/c-Met + saline (64) (Figure 7C). The gene discussed is AKT1; the disease is cancer.