Approximately 54% of differentially expressed genes found in the SB/AKT/c-Met + TAA versus SB/AKT/c-Met + saline or SB/AKT/c-Met + TAA versus SB + TAA comparisons were not altered by either cancer plasmids without TAA or TAA alone compared with negative control (Figure 7D; Supplementary Tables S5 and 6), while 48% of genes found for similar comparisons with SB/AKT/NRas were unique to the cancer plasmids-TAA combination (Figure 7E; Supplementary Tables S7 and 8). The gene discussed is NRAS; the disease is cancer.