The Cox regression models, adjusting for non‐imaging covariates (i.e., age, sex, education, race, APOE4), showed that NC participants with MBI had a 2.83‐fold higher hazard (95% CI: [1.80, 4.44], p < .001) for developing MCI or dementia compared to No NPS. The gene discussed is APOE; the disease is dementia.