Therapeutic efficacy of its parent molecule HAMLET (Human Alpha‐lactalbumin Made LEthal to Tumor cells) has been documented in animal models of colon cancer, bladder cancer and glioblastoma, and clinical effects have been reported in patients with bladder cancer or skin papillomas.12, 13, 14, 15, 16, 17. The gene discussed is LALBA; the disease is urinary bladder cancer.