NEFL and Mental deterioration: Similarly, we observed that higher baseline plasma levels of P-tau181 (β = −0.42, p = 5.45 × 10−4), NfL (β = −0.26, p = 0.03), and GFAP (β = −0.52, p = 1.38 × 10−5) were associated with faster cognitive decline, but not baseline Aβ42/Aβ40 ratio (β = 0.11, p = 0.35) (Supplementary Table S2, Supplementary Figure S2).