This phenomenon was first described in female mice injected splenocytes from allogeneic mice (12), and later in allo-HSCT mouse models (11, 13), in which ovarian disorders caused by GVHD following allo-HSCT were described as atrophic volumes (13), decreased AMH (11, 13), fewer numbers of retrieved oocytes upon superovulation (11), or induced ovulation (13), as well as lower numbers of naturally conceived newborns (11, 13) compared with syngeneic transplantation. This evidence concerns the gene AMH and graft versus host disease.