IL10 and diabetes mellitus: It has been demonstrated that some gut bacteria influence the initiation of DM while some are capable of stimulating anti-inflammatory responses that help the protection against DM development.77 The bacteria Bacteroidesfragilis, Roseburiaintestinalis, Akkermansiamuciniphila, L. fermentum, L. plantarum, L. casei have been reported to improve the metabolism of glucose by inducing the expression of IL-10.