Although the effects of the probiotics on T2D are inconsistent, evidence from animal investigations confirmed the efficient role of probiotics in glucose metabolism and increasing cellular sensitivity to insulin.11 Administration of probiotics is reported to efficiently decrease fasting blood glucose (FBG), glycosylated hemoglobin (HbA1c), and insulin resistance, which are critical indicators for glucose metabolism deficiencies.12 This evidence concerns the gene INS and type 2 diabetes mellitus.