IL6 and coronary artery disorder: The results of a meta-analysis study (2021) reported that the administration of pre-procedure trimetazidine may have a role in reducing periprocedural myocardial injury in patients with CAD undergoing PCI.25 Shah et al study (2020) showed that acute preprocedural administration of colchicine reduced the increase in interleukin-6 and hs-CRP concentrations after PCI when compared with placebo but did not lower the risk of PCI-related myocardial injury.26