Despite this fact, the impact of FTO variants has been a subject of controversy among oceanic, Egyptian, Portuguese, Iranian, Brazilian and other multi-ethnic populations.9,12,13,26,36,37 The present investigation has reported a significant association of 30685GG and -23525AA genotypes with the risk of obesity and its related parameters in the studied population. The gene discussed is FTO; the disease is obesity due to melanocortin 4 receptor deficiency.