Specifically, elevation in IGFBP-2 (OR: 1.2151, 95% CI: 1.0122-1.4587, PIVW: 0.0366), omentin (OR: 1.2176, 95% CI: 1.0037-1.4770, PIVW: 0.0458), TECK (OR: 1.1165, 95% CI: 1.0053-1.2399, PIVW: 0.0395), and THP (OR: 1.2977, 95% CI: 1.0325-1.6310, PIVW: 0.0255) was associated with an increased risk of herpes zoster. This evidence concerns the gene CCL25 and herpes zoster.