The bottom profile exclusively corresponds to proteins up in the cancer group, with notable colon cancer proteins such as TMEM173 (or STING, stimulator of interferon genes),40 PARP1 (poly ADP-ribose polymerase-1),41,42 and RAB25 (Ras-related protein Rab-25).43 The gene discussed is PARP1; the disease is malignant colon neoplasm.