By contrast, no significant difference was observed in the sex, age, pathological category, body mass index (BMI), smoking behavior, alcohol behavior, stage, AST/ALT ratio levels, anti-angiogenic therapy, bone metastasis and liver disease (including liver metastasis, hepatic cysts, fatty liver, chronic hepatitis, liver rupture, and so on) between ICIs-nonRT and iRT groups (Table 1). The gene discussed is GPT; the disease is bone metastasis.